Effects of LytR on bacterial morphology in Streptococcus pyognes

A robust cell envelope is the first line of defense in infectious pathogens when encountering host immune defenses. In Gram-positive bacteria, LytR-CpsA-Psr (LCP) family proteins play a major role synthesis and assembly envelope. The bacterium S. pyogenes causes wide range diseases from pharyngitis to septicemia, but involvement LytR wall this not clear. Therefore, we investigated whether pyogenes, like other streptococci, involved formation. lytR gene-deficient strains were used investigate bacteria's ability form chaining, drug sensitivity penicillin G, an inhibitor synthesis, bacterial biofilm formation, morphological structure bacteria by transmission electron microscopy, expression pbp2b, which encodes penicillin-binding protein, compared with wild-type strain. Our results showed that LytR-deficient had reduced chaining strains. Compared strains, also more sensitive G. This genetic study was accompanied increased pbp2b gene addition, strain biofilms, irregularities abnormal septa. These indicate pyognes.